Trenbolone (trenbolone acetate)
Trenbolone is arguably the most powerful injectable anabolic steroid that Steroid.com members use to gain muscle mass. However, the properties of this drug are not always fully known. This profile will separate fact from fiction and help Steroid.com members decide if Trenbolone is right for them.
Trenbolone is similar to the very popular steroid nandrolone in that they are both 19 as steroids, meaning that the testosterone molecule has been modified at position 19 to create a new compound. However, unlike nandrolone, trenbolone is great for weight gain and muscle building, which is achieved at the expense of muscle fiber with minimal water retention. It has an incredible anabolic (muscle building) value of 500. If you compare this to testosterone, which is itself a powerful mass builder and has an anabolic value of 100, you can understand the potential of trenbolone for building muscle mass. What makes trenbolone so anabolic? Many factors play a role. Trenbolone significantly increases the levels of the highly anabolic hormone IGF-1 in muscle tissue. In addition, it is worth mentioning that not only does it more than double the amount of IGF-1 in the muscle, but it also increases the sensitivity of muscle satellite cells (the cells that repair damaged muscle) to IGF-1 and other growth factors. The amount of DNA per muscle cell can also increase significantly.
Trenbolone also binds very strongly to the androgen receptor (AR), much more than testosterone. This is important because the more a steroid binds to the androgen receptor, the more it is able to activate AR-dependent muscle growth mechanisms. There is also compelling evidence that compounds that bind very strongly to the androgen receptor also promote fat loss. Think of receptors as locks and androgens as different keys, with some keys (androgens) opening (binding) the locks (receptors) much better than others. This does not mean that AR binding is the last word in steroid effectiveness. Anadrol has no measurable relationship with AR, and we all know how effective anadrol is at gaining mass.
Effects of the drug on the body
Trenbolone increases nitrogen storage in muscle tissue. This is important because nitrogen retention is a strong indicator of how anabolic a substance is. But the incredible mass-building effects don’t stop there. Trenbolone can bind to anti-anabolic (muscle-degrading) glucocorticoid hormone receptors. It can also inhibit cortisol, a catabolic (muscle-destroying) hormone.
Another surprising property is its ability to improve food conversion and mineral absorption in animals to which it is administered. To give you an idea of what this means to you, feed efficiency is an indicator of the amount of food converted into meat, and the more food needed to produce meat, the lower the efficiency. Conversely, the less feed required for meat production, the higher the efficiency. Trenbolone-treated animals gained weight without changing their diet, which increased feed efficiency. The food ingested is better used to build muscle mass and vitamins and minerals are better absorbed, allowing them to stay healthy during the cycle.
Trenbolone is also a highly androgenic hormone compared to testosterone, which has an androgenic ratio of 100; the androgenic ratio of trenbolone is a staggering 500. Little is known about the fact that androgen receptors are found in both fat cells and muscle cells, that androgens act directly on the AR of fat cells, and that they have a fat-burning effect: The more androgens bind to the AR, the greater the lipolytic (fat-burning) effect on fat tissue. Since some steroids even increase the RA of muscle and fat, this fat-burning effect can be enhanced by the combined use of other compounds such as testosterone.
Trenbolone stimulates red blood cell production and increases the rate of glycogen replenishment, which greatly improves recovery.
Chemical storage of trenbolone
The chemical structure of trenbolone makes it resistant to aromatic enzymes (conversion to estrogen), so absolutely no percentage of trenbolone is converted to estrogen. Taking trenbolone will not contribute to estrogenic side effects such as breast tissue growth in men (gynecomastia, pimples), accelerated fat accumulation, decreased fat breakdown, and water retention. Trenbolone is also resistant to the enzyme 5-alpha reductase, this enzyme restores some steroid hormones to a more androgenic form, but in this case it is not essential. Trenbolone boasts an androgenic ratio of 500. In people prone to hair loss, prostate enlargement, oily skin and acne, it can easily cause unwanted androgenic side effects. Unfortunately, trenbolone’s potential negative side effects don’t end there.
Testicular atrophy (ball shrinkage) may also occur; taking hCG intermittently during the cycle can prevent this. Tren users are also advised to carefully monitor cholesterol levels, kidney function, and liver enzymes, as Tren can adversely affect all of these functions. Finaplex, as a potent progestin, also suppresses natural testosterone production, so even at a relatively low dose and for an extended period of time, it maintains reduced testosterone levels, which can reduce libido and lead to erectile dysfunction (fina dick).
The acetate ester is a complex ester with a very short chain attached to the finaplex molecule.
Its active life is 2-3 days, but daily injections are often recommended to maintain high and stable levels of trenbolone in the blood. Acetate ester provides a rapid and high concentration of the hormone which is beneficial for those who want rapid progression coupled with a fast elimination time, acetate ester can be stopped if unwanted side effects occur.
Now that trenbolone acetate’s properties have been explained, we can better understand how to use it to maximize its benefits. Evidence shows that Finaplix in combination with estrogen promotes greater weight gain than trenbolone alone, now I’m not telling you to use contraceptives with your Tren, but adding a flavored oral drug like Dianabol and a long complex testosterone like Cypionate or Enanthate will give great results in a weight gain cycle.
Finaplix is the best choice for a cutting cycle; trenbolone’s powerful effect on nutrient movement allows the user to restrict calories and maintain a positive nitrogen balance (remember what that means?). Winstrol can be used alongside Tren in a cutting cycle. Winstrol has a low binding affinity for AR and so will act completely differently in your body than Tren (i.e. no receptor-mediated action). Also, Winstrol is a DHT based drug and Tren is 19-nor with the addition of some testosterone (support) and you will have a cutting cycle that uses all 3 major families of anabolic steroids (testosterone, 19-nor, and DHT) and completely different AR binding properties and mechanisms of action (non-receptor mediated actions). Also, Winstrol is a DHT based drug, and Tren is 19-nor, which adds a bit of testosterone (support), and you’ll have a cutting cycle that uses all 3 major families of anabolic steroids (testosterone, 19-nor, and DHT) as well as completely different AR binding properties and mechanisms of action.
Winstrol is also a DHT based drug, and Tren is a 19-nor that adds a little testosterone (support), and you will have a cutting cycle that uses all 3 major families of anabolic steroids (testosterone, 19-nor) and DHT), as well as very different AR binding properties and mechanisms of action.